Colorectal Cancer

01 — Colorectal Cancer

Overview

Colorectal cancer affects the colon or rectum and often develops from abnormal growths called polyps. The disease can vary considerably depending on its location, stage and biological characteristics.

Medical oncology may form part of treatment before or after surgery, or may become central to care when the disease has spread or returned. Early assessment and accurate staging help the cancer team determine the most appropriate treatment strategy.

  • Where it startsColon or rectum, often from polyps
  • Varies byLocation, stage and biological characteristics
  • Medical oncologyBefore or after surgery, or central in advanced disease

02 — Colorectal Cancer

Common Signs & Symptoms

  • 01Persistent changes in bowel habits
  • 02Blood in or on the stool
  • 03Abdominal discomfort, cramps or bloating
  • 04Unexplained weight loss
  • 05Persistent tiredness or weakness
  • 06A feeling that the bowel does not empty completely

These signs do not always mean cancer, but any new or persistent symptom should be assessed by a doctor.

03 — Colorectal Cancer

Diagnosis & Staging

Diagnosis may involve clinical assessment, blood tests, colonoscopy and biopsy. Imaging and other investigations may then be used to determine the extent of disease and establish the stage. Pathology provides important information about the tumour, while molecular testing may provide additional information relevant to treatment planning. The complete assessment helps determine whether medical oncology, surgery, radiation therapy or a combination of treatments is appropriate.

  1. 1

    Clinical assessment & blood tests

    The initial evaluation of symptoms and general health.

  2. 2

    Colonoscopy

    Examination of the colon and rectum.

  3. 3

    Biopsy

    Used to obtain a tissue sample for diagnosis.

  4. 4

    Imaging & staging investigations

    Determine the extent of disease and establish the stage.

  5. 5

    Pathology & molecular testing

    Provide information about the tumour that is relevant to treatment planning.

04 — Colorectal Cancer

Treatment Options

Treatment depends on whether the cancer is in the colon or rectum and on its stage. Options can include surgery, chemotherapy, radiation therapy, targeted therapy and immunotherapy. Different treatments may be combined or used at different stages of care, including before or after surgery or for advanced disease.

Surgery

May be combined with other treatments or used at different stages of care.

Radiation therapy

May be combined with other treatments or used at different stages of care.

Systemic treatments

  • Chemotherapy
  • Targeted therapy
  • Immunotherapy

When treatments may be given

  • Before surgery
  • After surgery
  • For advanced disease

The treatment plan is tailored to the individual cancer and the patient’s overall clinical condition.

Dr. Pranay Girdhari Taori
Dr. Pranay Girdhari TaoriSpecialist Medical Oncologist

05 — Colorectal Cancer

Dr. Taori’s Approach

Dr. Taori has participated in colorectal cancer awareness and professional education, including a colorectal cancer health-awareness programme at Zulekha Hospital. His medical oncology approach considers the stage and characteristics of the cancer when determining the role of systemic treatment. He coordinates treatment with the appropriate multidisciplinary team when surgery, radiation or other specialist care is involved. This helps ensure that medical oncology forms part of a coordinated overall plan.

  • Considers the stage and characteristics of the cancer first
  • Coordinates with the multidisciplinary team
  • Medical oncology as part of a coordinated overall plan

06 — Colorectal Cancer

Consultation

If you have symptoms, a new diagnosis or questions about an existing colorectal cancer treatment plan, a specialist oncology consultation can provide individualised guidance. Dr. Taori can review the diagnosis and explain the medical treatment options relevant to your situation.